Library/Health Professions and Related Programs/Guyton and Hall Textbook of Medical Physiology, 14th Edition/Organization of the Nervous System, Basic Functions of Synapses, and Neurotransmitters

Organization of the Nervous System, Basic Functions of Synapses, and Neurotransmitters

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Questions

Question 1

What is the term for a prolonged output discharge from a neuronal pool that lasts from a few milliseconds to many minutes after the incoming signal has ended?

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Question 2

What is the cause of signal prolongation in a reverberatory or oscillatory circuit?

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Question 3

In a complex reverberating circuit as shown in Figure 47-14C, what is the effect of a facilitatory signal?

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Question 4

What is the primary cause for the sudden cessation of signal output from a typical reverberatory circuit?

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Question 5

What are the two primary mechanisms that can cause some neuronal circuits to emit output signals continuously, even without excitatory input signals?

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Question 6

In the 'carrier wave' type of information transmission, what is the function of excitatory and inhibitory control signals?

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Question 7

According to Figure 47-17, what effect does progressively increasing stimulation of the carotid body have on the rhythmical output of the phrenic nerve?

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Question 8

What are the two fundamental mechanisms that the central nervous system uses to prevent the excessive spread of signals and maintain stability?

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Question 9

What is the term for synaptic transmission becoming progressively weaker as the period of excitation becomes more prolonged and intense?

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Question 10

What is the long-term consequence of overactivity at a synapse on its receptor proteins?

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Question 11

How does a synaptic afterdischarge mechanism allow a single instantaneous input signal to cause a sustained output?

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Question 12

What characteristic distinguishes the reverberatory circuit in Figure 47-14B from the one in Figure 47-14A?

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Question 13

According to the text, what determines whether the total reverberating signal in a system with many parallel fibers (Figure 47-14D) is weak or strong?

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Question 14

How long can the output from a typical reverberatory circuit last, even if the input stimulus lasts for only 1 millisecond?

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Question 15

In which parts of the nervous system does the phenomenon of continuous intrinsic neuronal discharge particularly occur?

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Question 16

What type of information transmission, used by the autonomic nervous system to control functions like vascular tone, allows for both an increase and a decrease in signal intensity?

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Question 17

What is the identified cause for almost all rhythmical signals that have been studied experimentally, such as the respiratory signal?

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Question 18

Which type of inhibitory circuit returns signals from the termini of pathways back to inhibit the initial excitatory neurons of the same pathways?

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Question 19

According to Figure 47-18, what is the effect of shortening the interval between successive flexor reflexes?

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Question 20

What is the long-term mechanism by which the sensitivity of a synapse is increased when there is prolonged underactivity?

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Question 21

What cellular machinery is responsible for constantly forming the receptor proteins that are inserted into a neuron's synaptic membrane?

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Question 22

What is synaptic afterdischarge?

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Question 23

What is the simplest variety of a reverberatory circuit, as shown in Figure 47-14A?

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Question 24

What typically happens to the intensity of the output signal from a reverberatory circuit immediately after a single input stimulus?

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Question 25

What is meant by 'continuous intrinsic neuronal discharge'?

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Question 26

In the context of stabilizing nervous system function, what is the role of synaptic fatigue?

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Question 27

What is the consequence for synaptic receptors when synapses are overused, causing an excess of transmitter substance to combine with them?

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Question 28

What is the primary characteristic of the simplest reverberatory circuit shown in Figure 47-14A?

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Question 29

In a reverberatory circuit, how can the duration of the total signal before cessation be controlled?

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Question 30

What is the effect of an inhibitory signal on a reverberating circuit?

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Question 31

Which of the following is an example of a system that uses a 'carrier wave' type of information transmission?

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Question 32

What does synaptic fatigue cause in an overused neuronal pathway according to the principle of automatic short-term adjustment?

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Question 33

What is the term for a prolonged output discharge from a neuronal pool that occurs after the incoming signal has ceased?

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Question 34

What type of afterdischarge is caused by the development of a postsynaptic electrical potential that lasts for many milliseconds?

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Question 35

In a reverberatory circuit, what is the role of positive feedback?

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Question 36

What is the typical pattern of an output signal from a reverberatory circuit as depicted in Figure 47-15?

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Question 37

Which mechanism allows certain neurons, like many in the cerebellum, to emit impulses continually even without excitatory input?

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Question 38

What is the primary cause of instability in neuronal circuits that could lead to effects like epileptic seizures?

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Question 39

How do neuronal pools that exert gross inhibitory control, such as the basal ganglia, contribute to nervous system stability?

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Question 40

What is the primary effect of synaptic fatigue on synaptic transmission?

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Question 41

How does the nervous system achieve long-term changes in synaptic sensitivity?

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Question 42

What is the condition for upregulation of receptor proteins at a synaptic site?

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Question 43

An afterdischarge lasting for many milliseconds due to a long-acting synaptic transmitter causing a sustained postsynaptic potential is known as what?

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Question 44

In a complex system like that shown in Figure 47-14C, what is the role of an inhibitory fiber impinging on the reverberating circuit?

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Question 45

What physiological process underlies the 'carrier wave' type of information transmission?

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Question 46

How does a reverberating circuit that does not fatigue sufficiently to stop its activity function as a means for transmitting information?

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Question 47

What is the primary significance of the 'carrier wave' system of information transmission compared to systems that only transmit positive information?

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Question 48

What is the general cause of rhythmical signal outputs, such as those for respiration or scratching movements?

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Question 49

What mechanism of short-term sensitivity adjustment is described as being constituted by fatigue and recovery from fatigue?

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Question 50

What is the effect of prolonged underactivity on the number of receptor proteins at a synapse?

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