The Body Fluid Compartments: Extracellular and Intracellular Fluids; Interstitial Fluid and Edema
50 questions available
Questions
What is the primary factor that determines the distribution of fluid between the intracellular and extracellular compartments?
View answer and explanationWhat is the calculated osmolarity in mOsm/L of a 0.9 percent sodium chloride solution, before applying the osmotic coefficient?
View answer and explanationWhat happens to a cell when it is placed in a hypotonic solution with a lower concentration of impermeant solutes?
View answer and explanationWhat is the primary difference between the terms 'isotonic' and 'isosmotic'?
View answer and explanationWhat is the main effect of adding an isotonic saline solution to the extracellular fluid compartment?
View answer and explanationAccording to the calculation example in the text, what is the approximate final extracellular fluid volume after infusing 2 liters of a 3.0 percent hypertonic sodium chloride solution into a 70-kg patient with an initial ECF volume of 14 liters?
View answer and explanationWhat is the primary cellular-level consequence of rapid hyponatremia, particularly in the brain?
View answer and explanationA condition characterized by the presence of excess fluid in the body tissues, which can involve both extracellular and intracellular compartments, is known as what?
View answer and explanationWhich of the following conditions is a primary cause of intracellular edema?
View answer and explanationWhat are the two general causes of extracellular edema?
View answer and explanationWhat is the term for a solution that will cause cells to shrink because it has a higher concentration of impermeant solutes?
View answer and explanationWhat is the approximate osmolarity of a 5 percent glucose solution, making it nearly isotonic?
View answer and explanationWhat is the net effect of adding a hypertonic solution to the extracellular fluid?
View answer and explanationAccording to the text, what percentage of the total osmolarity of the interstitial fluid and plasma is due to sodium and chloride ions?
View answer and explanationWhat is the term for a reduced plasma sodium concentration, typically below 142 mEq/L?
View answer and explanationWhich of the following conditions can cause hypernatremia, an elevated plasma sodium concentration?
View answer and explanationWhat is the primary physiological effect of hypernatremia on the body's cells?
View answer and explanationIn the process of calculating fluid shifts after an infusion, what are the two fundamental principles that must be kept in mind?
View answer and explanationIn which part of the body do the diseases nephrotic syndrome and cirrhosis of the liver cause edema?
View answer and explanationWhat is the approximate potential osmotic pressure that can develop across a cell membrane if the cell, with an intracellular osmolarity of 282 mOsm/L, is exposed to pure water?
View answer and explanationLymphedema, a severe form of extracellular edema, is caused by the failure of which system?
View answer and explanationWhat is the term used to describe the type of edema where pressing a thumb against the tissue area leaves a pit for a few seconds?
View answer and explanationWhat is the total safety factor against edema, which represents the theoretical rise in capillary pressure that can be tolerated before marked edema occurs?
View answer and explanationWhat is the term for edema fluid that collects in a potential space like the abdominal cavity?
View answer and explanationWhat is the normal interstitial fluid hydrostatic pressure in the pleural cavity?
View answer and explanationWhat distinguishes nonpitting edema from pitting edema?
View answer and explanationWhich condition, leading to decreased plasma proteins, is described as a major cause of edema and involves damage to the membranes of the renal glomeruli?
View answer and explanationWhat is the average interstitial fluid hydrostatic pressure in loose subcutaneous tissues, and how does this act as a safety factor against edema?
View answer and explanationThe term for an effusion, or collection of excess fluid, specifically within the abdominal cavity is known as what?
View answer and explanationWhat is the reason that highly permeating substances like urea have little effect on intracellular volume under steady-state conditions?
View answer and explanationWhy is plasma osmolarity a reasonable indicator of a patient's fluid status in many clinical conditions?
View answer and explanationA patient with adrenal insufficiency and overuse of diuretics is likely to present with which combination of conditions according to Table 25-4?
View answer and explanationIn a patient with slowly developing hyponatremia, how does the brain attenuate swelling?
View answer and explanationWhat is the primary danger of correcting chronic hyponatremia too rapidly with hypertonic solutions?
View answer and explanationWhat is considered a common cause of hypernatremia associated with decreased extracellular fluid volume?
View answer and explanationWhy might a patient with Cushing disease or primary aldosteronism develop hypernatremia-overhydration?
View answer and explanationBelow what plasma protein concentration does serious generalized edema typically occur?
View answer and explanationHow does liver cirrhosis contribute to the formation of ascites?
View answer and explanationWhat is the role of interstitial gel, formed by a proteoglycan meshwork, in normal tissues?
View answer and explanationWhat is the safety factor against edema provided by the 'washdown of interstitial fluid protein'?
View answer and explanationHow does the increased ability of lymph flow act as a safety factor against edema?
View answer and explanationWhat is the osmotic coefficient of sodium chloride, and what does it account for?
View answer and explanationIn heart failure, what is the consequence of the heart failing to pump blood normally from the veins into the arteries regarding edema formation?
View answer and explanationWhat is the definition of osmolality?
View answer and explanationWhy does adding a hypotonic solution to the extracellular fluid cause a greater increase in intracellular volume than in extracellular volume?
View answer and explanationAn infection with filarial nematodes (Wuchereria bancrofti) causes severe edema primarily by which mechanism?
View answer and explanationAccording to the principles of osmosis, if a solute like sodium chloride is added to the extracellular fluid, what is the immediate response of water?
View answer and explanationWhat is the primary reason for correcting the calculated osmolarity of a sodium chloride solution with an osmotic coefficient?
View answer and explanationWhich of the following is NOT listed as one of the three conditions especially prone to cause intracellular swelling (edema)?
View answer and explanationIn the summary of safety factors that prevent edema, what is the value of the safety factor caused by increased lymph flow?
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