Behavioral and Motivational Mechanisms of the Brain—The Limbic System and the Hypothalamus
50 questions available
Questions
What is the primary function of the lateral nuclei of the hypothalamus in the regulation of food intake?
View answer and explanationWhat is the consequence of destroying the ventromedial nuclei of the hypothalamus?
View answer and explanationWhat is the primary effect of activating pro-opiomelanocortin (POMC) neurons in the arcuate nuclei of the hypothalamus?
View answer and explanationWhich hormone is released mainly by the stomach, rises during fasting, and stimulates orexigenic neurons in the hypothalamus to increase food intake?
View answer and explanationWhat is the primary role of agouti-related protein (AGRP) released from orexigenic neurons in the hypothalamus?
View answer and explanationWhich hormone, released from adipocytes, circulates to the brain to signal that sufficient energy has been stored, thereby inhibiting food intake?
View answer and explanationWhat is the primary mechanism by which gastrointestinal filling inhibits feeding?
View answer and explanationAccording to the body mass index (BMI) classification, what range is considered overweight?
View answer and explanationIn the context of starvation, what is the primary cause of the initial, rapid depletion of protein stores?
View answer and explanationWhat is cachexia primarily defined as?
View answer and explanationWhat is the primary role of the amygdala in controlling food intake?
View answer and explanationThe release of which gastrointestinal hormone, mainly in response to fat and proteins entering the duodenum, contributes to short-term satiation and meal cessation?
View answer and explanationAccording to the provided text, what percentage of obesity cases may be caused by genetic factors?
View answer and explanationWhat is the most common known monogenic (single-gene) cause of human obesity?
View answer and explanationDuring prolonged starvation, what proportion of the brain's energy can be derived from ketone bodies?
View answer and explanationWhat is the primary role of neuropeptide Y (NPY) released by neurons in the arcuate nuclei?
View answer and explanationIn the United States, what waist circumference is often considered an indicator of abdominal obesity in women?
View answer and explanationWhich neural centers are primarily responsible for controlling the actual mechanics of feeding, such as salivation, chewing, and swallowing?
View answer and explanationWhat is the term for the condition where extreme weight loss is caused by inadequate availability of food or by pathophysiological conditions that decrease the desire for food?
View answer and explanationWhich of the following is considered a key factor in the short-term regulation of food intake, helping to prevent overeating at each meal?
View answer and explanationObesity is typically defined as having a total body fat percentage greater than what value for men?
View answer and explanationWhat phenomenon suggests that the 'set points' for feeding and metabolic control are at a higher level of nutrient storage in an obese person?
View answer and explanationHow many excess calories of energy intake are required to store approximately 1 gram of fat?
View answer and explanationWhich of these is a function of neuropeptide Y (NPY) and agouti-related protein (AGRP) producing neurons in the hypothalamus?
View answer and explanationWhat is the primary characteristic of 'leptin resistance' as a potential cause of obesity?
View answer and explanationWhat effect does destruction of the lateral hypothalamus have on an animal's desire for food?
View answer and explanationWhat is the primary anorexigenic (appetite-suppressing) hormone produced by pro-opiomelanocortin (POMC) neurons?
View answer and explanationWhich condition is characterized by an abnormal psychic state where a person loses all desire for food and may even become nauseated by it?
View answer and explanationIn the United States, what waist circumference is often considered an indicator of abdominal obesity in men?
View answer and explanationObesity is defined as having a Body Mass Index (BMI) greater than or equal to what value?
View answer and explanationWhich two hypothalamic nuclei are particularly important as controllers of both appetite and energy expenditure, containing POMC and NPY/AGRP neurons?
View answer and explanationWhat is the primary effect of the gastrointestinal hormone peptide YY (PYY)?
View answer and explanationWhat is the primary difference between hyperplastic obesity and hypertrophic obesity?
View answer and explanationWhat role does glucagon-like peptide (GLP) play in regulating appetite?
View answer and explanationAn extremely obese person may have up to how many times the number of adipocytes as a lean person?
View answer and explanationWhat is the primary cause for the increased prevalence of obesity in the last few decades, according to the text?
View answer and explanationWhat are the two major classes of substances categorized by their effect on feeding behavior?
View answer and explanationWhat is the primary role of the long-term regulatory system for feeding?
View answer and explanationApproximately 80 percent of children who are obese become what?
View answer and explanationWhat is the 'psychic blindness' that occurs after destruction of the amygdala related to?
View answer and explanationWhich of the following is an example of an orexigenic substance listed in Table 72-2?
View answer and explanationWhich of the following is an example of an anorexigenic substance listed in Table 72-2?
View answer and explanationWhat is a major reason for the difficulty in achieving sustained weight loss through dieting alone?
View answer and explanationHow long do the hormonal changes that increase hunger, such as increased ghrelin and decreased leptin, persist after diet-induced weight loss?
View answer and explanationWhich inflammatory cytokines have been shown to cause anorexia and cachexia, particularly in the context of cancer?
View answer and explanationWhat is the primary purpose of the 'oxygen debt' that is repaid after strenuous exercise?
View answer and explanationWhat is the primary role of oral receptors in feeding regulation?
View answer and explanationWhat is the typical duration of the inhibitory effect on feeding caused by oral receptors?
View answer and explanationWhich of these is NOT listed as one of the five types of signals the hypothalamus receives to regulate feeding behavior?
View answer and explanationWhat is the primary physiological basis for treating obesity with gastric bypass or gastric banding surgery?
View answer and explanation