Library/Health Professions and Related Programs/Guyton and Hall Textbook of Medical Physiology, 14th Edition/Behavioral and Motivational Mechanisms of the Brain—The Limbic System and the Hypothalamus

Behavioral and Motivational Mechanisms of the Brain—The Limbic System and the Hypothalamus

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Questions

Question 1

What is the primary function of the lateral nuclei of the hypothalamus in the regulation of food intake?

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Question 2

What is the consequence of destroying the ventromedial nuclei of the hypothalamus?

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Question 3

What is the primary effect of activating pro-opiomelanocortin (POMC) neurons in the arcuate nuclei of the hypothalamus?

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Question 4

Which hormone is released mainly by the stomach, rises during fasting, and stimulates orexigenic neurons in the hypothalamus to increase food intake?

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Question 5

What is the primary role of agouti-related protein (AGRP) released from orexigenic neurons in the hypothalamus?

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Question 6

Which hormone, released from adipocytes, circulates to the brain to signal that sufficient energy has been stored, thereby inhibiting food intake?

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Question 7

What is the primary mechanism by which gastrointestinal filling inhibits feeding?

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Question 8

According to the body mass index (BMI) classification, what range is considered overweight?

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Question 9

In the context of starvation, what is the primary cause of the initial, rapid depletion of protein stores?

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Question 10

What is cachexia primarily defined as?

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Question 11

What is the primary role of the amygdala in controlling food intake?

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Question 12

The release of which gastrointestinal hormone, mainly in response to fat and proteins entering the duodenum, contributes to short-term satiation and meal cessation?

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Question 13

According to the provided text, what percentage of obesity cases may be caused by genetic factors?

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Question 14

What is the most common known monogenic (single-gene) cause of human obesity?

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Question 15

During prolonged starvation, what proportion of the brain's energy can be derived from ketone bodies?

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Question 16

What is the primary role of neuropeptide Y (NPY) released by neurons in the arcuate nuclei?

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Question 17

In the United States, what waist circumference is often considered an indicator of abdominal obesity in women?

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Question 18

Which neural centers are primarily responsible for controlling the actual mechanics of feeding, such as salivation, chewing, and swallowing?

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Question 19

What is the term for the condition where extreme weight loss is caused by inadequate availability of food or by pathophysiological conditions that decrease the desire for food?

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Question 20

Which of the following is considered a key factor in the short-term regulation of food intake, helping to prevent overeating at each meal?

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Question 21

Obesity is typically defined as having a total body fat percentage greater than what value for men?

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Question 22

What phenomenon suggests that the 'set points' for feeding and metabolic control are at a higher level of nutrient storage in an obese person?

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Question 23

How many excess calories of energy intake are required to store approximately 1 gram of fat?

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Question 24

Which of these is a function of neuropeptide Y (NPY) and agouti-related protein (AGRP) producing neurons in the hypothalamus?

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Question 25

What is the primary characteristic of 'leptin resistance' as a potential cause of obesity?

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Question 26

What effect does destruction of the lateral hypothalamus have on an animal's desire for food?

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Question 27

What is the primary anorexigenic (appetite-suppressing) hormone produced by pro-opiomelanocortin (POMC) neurons?

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Question 28

Which condition is characterized by an abnormal psychic state where a person loses all desire for food and may even become nauseated by it?

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Question 29

In the United States, what waist circumference is often considered an indicator of abdominal obesity in men?

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Question 30

Obesity is defined as having a Body Mass Index (BMI) greater than or equal to what value?

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Question 31

Which two hypothalamic nuclei are particularly important as controllers of both appetite and energy expenditure, containing POMC and NPY/AGRP neurons?

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Question 32

What is the primary effect of the gastrointestinal hormone peptide YY (PYY)?

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Question 33

What is the primary difference between hyperplastic obesity and hypertrophic obesity?

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Question 34

What role does glucagon-like peptide (GLP) play in regulating appetite?

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Question 35

An extremely obese person may have up to how many times the number of adipocytes as a lean person?

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Question 36

What is the primary cause for the increased prevalence of obesity in the last few decades, according to the text?

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Question 37

What are the two major classes of substances categorized by their effect on feeding behavior?

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Question 38

What is the primary role of the long-term regulatory system for feeding?

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Question 39

Approximately 80 percent of children who are obese become what?

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Question 40

What is the 'psychic blindness' that occurs after destruction of the amygdala related to?

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Question 41

Which of the following is an example of an orexigenic substance listed in Table 72-2?

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Question 42

Which of the following is an example of an anorexigenic substance listed in Table 72-2?

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Question 43

What is a major reason for the difficulty in achieving sustained weight loss through dieting alone?

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Question 44

How long do the hormonal changes that increase hunger, such as increased ghrelin and decreased leptin, persist after diet-induced weight loss?

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Question 45

Which inflammatory cytokines have been shown to cause anorexia and cachexia, particularly in the context of cancer?

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Question 46

What is the primary purpose of the 'oxygen debt' that is repaid after strenuous exercise?

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Question 47

What is the primary role of oral receptors in feeding regulation?

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Question 48

What is the typical duration of the inhibitory effect on feeding caused by oral receptors?

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Question 49

Which of these is NOT listed as one of the five types of signals the hypothalamus receives to regulate feeding behavior?

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Question 50

What is the primary physiological basis for treating obesity with gastric bypass or gastric banding surgery?

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