Sensory Receptors, Neuronal Circuits for Processing Information

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Questions

Question 1

What two neurotransmitters are released by Type C pain fiber terminals when they enter the spinal cord?

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Question 2

How does the release and duration of action of substance P compare to that of glutamate from pain fiber terminals?

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Question 3

According to the text, what is the proposed explanation for the “double” pain sensation felt after a pinprick?

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Question 4

What percentage of fibers from the slow-chronic paleospinothalamic pathway pass all the way to the thalamus?

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Question 5

Where do most fibers of the paleospinothalamic pathway terminate within the brain stem?

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Question 6

What is the primary role of the cerebral cortex in the appreciation of pain?

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Question 7

Why is it almost impossible for a person to sleep when in severe pain?

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Question 8

For what reason is a cordotomy, a surgical procedure to relieve pain, not always successful?

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Question 9

What are the three major components of the brain's analgesia system?

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Question 10

In the brain's analgesia system, what neurotransmitter is released by nerve fibers originating in the raphe magnus nucleus into the dorsal horns of the spinal cord?

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Question 11

What is the role of enkephalin in the dorsal horns of the spinal cord for pain suppression?

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Question 12

The body's natural opiate-like substances, such as endorphins and enkephalins, are all breakdown products of which three large protein molecules?

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Question 13

What is the proposed mechanism that explains why rubbing the skin near a painful area is often effective in relieving pain?

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Question 14

According to the probable mechanism of referred pain, what is the relationship between visceral pain fibers and skin pain fibers in the spinal cord?

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Question 15

Why does highly localized damage to a viscus, such as a surgeon's cut, seldom cause severe pain?

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Question 16

Visceral pain originating in the thoracic and abdominal cavities is primarily transmitted through which type of nerve fibers?

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Question 17

In general, how is visceral pain referred to the surface of the body?

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Question 18

Pain from the heart is typically referred to which areas because its visceral pain fibers enter the spinal cord between segments C3 and T5?

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Question 19

What is the cause of the severe pain associated with herpes zoster, also known as shingles?

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Question 20

In Brown-Séquard syndrome, where the spinal cord is transected on one side, why are sensations of pain and temperature lost on the opposite side of the body?

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Question 21

Which of the following structures inside the cranial vault is considered almost totally insensitive to pain?

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Question 22

Pain stimuli from beneath the tentorium, such as in the posterior fossa, cause what is known as an 'occipital headache' referred to which part of the head?

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Question 23

One theory of migraine headaches proposes that prolonged emotion or tension leads to what initial vascular event?

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Question 24

Which type of sensory receptors are responsible for discriminating thermal gradations, along with pain receptors at extreme temperatures?

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Question 25

In most areas of the body, how does the number of cold spots compare to the number of warmth spots?

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Question 26

What type of nerve fiber is primarily responsible for transmitting warmth signals?

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Question 27

According to the receptor stimulation graph, at what temperature do the cold receptors begin to be stimulated and reach their peak stimulation?

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Question 28

What paradoxical event happens to some cold fibers at temperatures around 45 degrees Celsius?

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Question 29

What is the primary mechanism believed to be responsible for the stimulation of thermal receptors?

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Question 30

How do thermal senses respond to a change in temperature compared to a steady-state temperature?

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Question 31

What is the minimum rapid temperature change that can be detected if it affects the entire surface of the body simultaneously?

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Question 32

Where do thermal signals terminate after entering the spinal cord and crossing to the opposite anterolateral sensory tract?

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Question 33

What is the effect of removing the entire cortical postcentral gyrus on a person's ability to distinguish gradations of temperature?

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Question 34

What are the two types of hyperalgesia described in the text?

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Question 35

In the dual transmission of pain from an inflamed appendix, what type of pain is referred to the area around the umbilicus?

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Question 36

What is the lancinating or stabbing type of pain that occurs over one side of the face in the sensory distribution of the fifth or ninth nerves called?

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Question 37

In addition to pain, what other symptom does the herpesvirus cause in shingles as it is carried by neuronal cytoplasmic flow to the cutaneous origins of the axon?

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Question 38

What is the primary characteristic of the paleospinothalamic pathway for slow-chronic pain that leads to its imprecision in localizing pain?

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Question 39

Electrical stimulation of which two areas, where slow-suffering pain terminates, has a strong arousal effect on the entire brain?

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Question 40

What is the location and function of the 'pain inhibitory complex' in the analgesia system?

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Question 41

In the brain's opiate system, where are the two enkephalins primarily found?

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Question 42

What is the key difference between the 'true visceral pathway' and the 'parietal pathway' for transmitting abdominal and thoracic pain?

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Question 43

Which visceral structures are described as being almost completely insensitive to pain?

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Question 44

Which condition is characterized by infection of a dorsal root ganglion, causing a segmental type of pain that circles halfway around the body?

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Question 45

In a patient with Brown-Séquard syndrome (spinal cord hemisection), which modalities of sensation are lost on the same side as the transection?

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Question 46

Stimulation of pain receptors in the cerebral vault above the tentorium causes referred headache to what area?

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Question 47

What is the primary proposed cause of an alcoholic headache?

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Question 48

What is the typical density of cold spots found in the skin of the lips?

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Question 49

Why might freezing cold and burning hot sensations feel almost alike when intense enough?

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Question 50

How do thermal signals travel within the spinal cord immediately after entering?

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