Library/Health Professions and Related Programs/Guyton and Hall Textbook of Medical Physiology, 14th Edition/Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction

Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction

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Questions

Question 1

What is the approximate total number of different proteins produced by the various cell types in humans, considering that RNA molecules can be processed in more than one way?

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Question 2

Which three basic chemical compounds are involved in the formation of DNA?

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Question 3

What is the term for the successive triplets of bases in the genetic code that control the sequence of amino acids in a protein molecule?

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Question 4

What is the name of the process where the genetic code from DNA in the nucleus is transferred to an RNA molecule?

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Question 5

Which pyrimidine base is used in RNA in place of thymine, which is found in DNA?

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Question 6

What is the function of transfer RNA (tRNA) in protein synthesis?

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Question 7

What is the role of ribosomes in the cell?

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Question 8

What is the total number of high-energy phosphate bonds from ATP that are used for each amino acid added to a protein chain during synthesis?

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Question 9

What is the name of the sequence of bases in a gene's promoter, typically 'TATAAA', that serves as a key binding site for transcription factors?

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Question 10

During which phase of the cell life cycle does the duplication of all DNA in the chromosomes occur?

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Question 11

What is the typical duration for the completion of DNA duplication before mitosis begins?

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Question 12

Which enzyme is responsible for joining the Okazaki fragments on the lagging strand to form a single unified DNA strand during replication?

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Question 13

What is the process called where special enzymes cut out defective areas of DNA and replace them with appropriate nucleotides after replication but before mitosis?

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Question 14

What is the term for the duplicated but still attached chromosomes that are held together at the centromere before mitosis?

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Question 15

During which stage of mitosis do the two asters of the mitotic apparatus get pushed farther apart, and the chromatids are pulled to the center of the cell to form the equatorial plate?

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Question 16

What is the role of telomeres in cell reproduction?

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Question 17

What is the process of programmed cell death, involving a specific proteolytic cascade, called?

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Question 18

What family of proteases is activated to initiate the process of apoptosis?

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Question 19

What is the term for normal genes that code for proteins controlling cell adhesion, growth, and division, but can cause cancer if mutated or excessively activated?

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Question 20

According to the text, which carcinogens are responsible for the greatest number of cancer deaths?

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Question 21

What is the primary function of MicroRNAs (miRNAs)?

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Question 22

What is the term for the process where introns are removed from pre-mRNA and exons are joined together?

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Question 23

What are clusters of 3 to 10 ribosomes attached to a single mRNA molecule at the same time called?

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Question 24

What type of chemical bond holds the two strands of the DNA helix together between the purine and pyrimidine bases?

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Question 25

What is the function of the enzyme peptidyl transferase in protein synthesis?

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Question 26

How many chromosomes are contained in a normal human cell?

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Question 27

What is the primary role of histone proteins in the nucleus?

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Question 28

Which stage of mitosis is characterized by the pulling apart of the two chromatids of each chromosome at the centromere?

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Question 29

What is the enzyme telomerase known for doing in certain cells like stem cells?

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Question 30

Cell differentiation in an embryo is believed to result primarily from what process?

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Question 31

How does an RNA virus, such as some oncoviruses, lead to cancer in an animal cell?

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Question 32

What is one of the key differences that distinguishes a cancer cell from a normal cell, regarding cell adhesion?

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Question 33

What enzyme is responsible for synthesizing an RNA molecule using a DNA strand as a template?

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Question 34

In the process of DNA replication, what is the role of the enzyme topoisomerase?

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Question 35

What term describes the process of forming a new cell having almost exactly the same structure as its progenitor?

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Question 36

What is the result of enzyme inhibition by a synthesized product on the first enzyme in a metabolic pathway?

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Question 37

What is the composition of the contractile ring that pinches a cell in two during telophase?

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Question 38

What happens to the mean electrical axis of the heart when a person lies down?

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Question 39

The process of a cell splitting into two new cells is called what?

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Question 40

What is the primary reason that a cardiac myocyte contains the same genetic code as a renal tubular epithelial cell, yet the two cells perform specialized, different functions?

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Question 41

How many amino acids are commonly found in protein molecules?

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Question 42

Which of the following is NOT a characteristic of cancer cells described in the text?

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Question 43

What is the function of small nuclear RNA (snRNA)?

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Question 44

During DNA replication, which strand is synthesized discontinuously in short pieces known as Okazaki fragments?

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Question 45

What is the typical resting membrane potential of a sinus nodal fiber, as compared to a ventricular muscle fiber?

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Question 46

The bond that links successive amino acids together in a protein chain is called a what?

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Question 47

What is the approximate duration of the life cycle for a highly stimulated mammalian bone marrow cell?

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Question 48

What is the term for a gene sequence that provides a barrier, isolating a specific gene from the transcriptional influences of surrounding genes?

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Question 49

How many genes are estimated to exist in the human body that code for proteins?

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Question 50

What is the primary way that cell activities are controlled through enzyme regulation?

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Other chapters

Functional Organization of the Human Body and Control of the “Internal Environment”The Cell and Its FunctionsTransport of Substances Through Cell MembranesMembrane Potentials and Action PotentialsContraction of Skeletal MuscleExcitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction CouplingExcitation and Contraction of Smooth MuscleCardiac Muscle; The Heart as a Pump and Function of the Heart ValvesRhythmical Excitation of the HeartThe Normal ElectrocardiogramCardiac Arrhythmias and Their Electrocardiographic InterpretationThe Circulation: Overview of the Circulation; Medical Physics of Pressure, Flow, and ResistanceVascular Distensibility and Functions of the Arterial and Venous SystemsThe Microcirculation and the Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph FlowLocal and Humoral Control of Tissue Blood FlowNervous Regulation of the Circulation and Rapid Control of Arterial PressureCardiac Output, Venous Return, and Their RegulationMuscle Blood Flow and Cardiac Output During Exercise; the Coronary Circulation and Ischemic Heart DiseaseCardiac FailureCirculatory Shock and Its TreatmentThe Body Fluid Compartments: Extracellular and Intracellular Fluids; Interstitial Fluid and EdemaUrine Formation by the Kidneys: I. Glomerular Filtration, Renal Blood Flow, and Their ControlUrine Formation by the Kidneys: II. Tubular Reabsorption and SecretionRenal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid VolumeRegulation of Acid-Base BalanceKidney Diseases and DiureticsRed Blood Cells, Anemia, and PolycythemiaResistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and InflammationResistance of the Body to Infection: II. Immunity and AllergyBlood Types; Transfusion; Tissue and Organ TransplantationHemostasis and Blood CoagulationPulmonary VentilationPrinciples of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through the Respiratory MembraneTransport of Oxygen and Carbon Dioxide in Blood and Tissue FluidsRespiratory Insufficiency—Pathophysiology, Diagnosis, Oxygen TherapyPhysiology of Deep-Sea Diving and Other Hyperbaric ConditionsOrganization of the Nervous System, Basic Functions of Synapses, and NeurotransmittersSensory Receptors, Neuronal Circuits for Processing InformationThe Eye: I. Optics of VisionThe Eye: II. Receptor and Neural Function of the RetinaCortical and Brain Stem Control of Motor FunctionContributions of the Cerebellum and Basal Ganglia to Overall Motor ControlCerebral Cortex, Intellectual Functions of the Brain, Learning, and MemoryBehavioral and Motivational Mechanisms of the Brain—The Limbic System and the HypothalamusStates of Brain Activity—Sleep, Brain Waves, Epilepsy, PsychosesThe Autonomic Nervous System and the Adrenal MedullaCerebral Blood Flow, Cerebrospinal Fluid, and Brain MetabolismGeneral Principles of Gastrointestinal Function—Motility, Nervous Control, and Blood CirculationPropulsion and Mixing of Food in the Alimentary TractSecretory Functions of the Alimentary TractMetabolism of Carbohydrates and Formation of Adenosine TriphosphateLipid MetabolismProtein MetabolismThe Liver as an OrganDietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and MineralsEnergetics and Metabolic RateBody Temperature Regulation and FeverIntroduction to EndocrinologyPituitary Hormones and Their Control by the HypothalamusThyroid Metabolic HormonesAdrenocortical HormonesInsulin, Glucagon, and Diabetes MellitusParathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth