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Questions

Question 1

What is the study of how drugs affect behavior, the brain, and the nervous system called?

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Question 2

What is the primary mechanism by which virtually all psychoactive drugs alter a person's feelings or thoughts?

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Question 3

What is the term for a drug that blocks a neurotransmitter's effect at the synapse?

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Question 4

Which drug is listed as an antagonist for dopamine (DA) and serotonin (5HT) receptors, and is used to treat schizophrenia and bipolar disorder?

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Question 5

What does the 'M' in the acronym ADME, used in pharmacokinetics, stand for?

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Question 6

Which two routes of drug administration are mentioned as being the most rapid, capable of getting a drug to the brain in less than 10 seconds?

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Question 7

According to the text, why does a drug that reaches the brain very quickly have a high risk for abuse and addiction?

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Question 8

What is the term for the process where repeated exposure to a drug like alcohol leads to an increase in the liver enzymes that break it down, requiring more of the drug to achieve the same effect?

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Question 9

How does grapefruit juice interact with the metabolism of certain psychotropic drugs?

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Question 10

Which of the following is NOT one of the four categories of drug metabolizers based on genetic differences in cytochrome P450 enzymes?

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Question 11

What is the likely outcome for a 'poor metabolizer' who is prescribed a standard daily dose of an antidepressant?

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Question 12

According to a recent Centers for Disease Control (CDC) report mentioned in the text, what fraction of children between the ages of 5 and 17 may have some type of mental disorder?

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Question 13

The text states that the incidence of which disorder in children and adolescents has increased 40 times in the past decade?

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Question 14

What is the primary concern scientists have regarding the use of psychotropic drugs in children and adolescents?

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Question 15

What is the term used to describe the use of multiple drugs, a practice very common in elderly populations?

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Question 16

By 2030, what percentage of all prescribed medications in the U.S. is it estimated that people aged 65 or older will consume?

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Question 17

Why are typical clinical trials for psychotropic drugs often problematic for interpreting results for an elderly population?

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Question 18

What happens to the metabolism of drugs in elderly populations, and what is a potential consequence?

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Question 19

Which neurotransmitter is primarily associated with reward circuits and is implicated in the action of psychostimulants like amphetamine?

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Question 20

What does the term 'pharmacokinetics' refer to?

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Question 21

Which route of drug administration is described as being the most dangerous due to the very little time available to administer an antidote in case of an adverse reaction?

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Question 22

What is 'metabolic tolerance'?

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Question 23

Besides depression, fluvoxamine (Luvox) is used to treat which other condition, according to the text?

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Question 24

What is the primary goal of the individualized treatment approach involving genetic testing for cytochrome P450 enzymes?

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Question 25

In the context of drug actions, what is a synapse?

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Question 26

What is the primary organ in the body responsible for drug metabolism?

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Question 27

Which category of drug metabolizer breaks down drugs more slowly than extensive metabolizers but faster than poor metabolizers?

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Question 28

What is one of the greatest risk factors for elderly populations mentioned in the text that can be exacerbated by psychotropic drug side effects like dizziness?

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Question 29

Besides dizziness, what other negative effect on the body can psychotropic medications have in older adults, worsening the consequences of a fall?

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Question 30

Which drug is listed in Table 2 as an agonist for Acetylcholine (ACh) and is used to treat Alzheimer's disease?

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Question 31

The text mentions that cues associated with drug use, such as a pipe for a crack user, can cause craving and lead to relapse. Why is this considered much more difficult for a cigarette smoker to avoid?

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Question 32

What is a psychotropic drug?

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Question 33

What is the key difference between a psychotropic drug and a psychoactive drug, as defined in the vocabulary section?

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Question 34

According to the text, why might pharmacotherapy combined with psychological therapy be the most beneficial treatment approach for many psychiatric conditions?

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Question 35

What is the primary reason that it is important to realize that most psychoactive drugs have effects on multiple neurotransmitters?

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Question 36

Which neurotransmitter is described in Table 1 as the 'Major excitatory neurotransmitter in the brain'?

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Question 37

Revia (naltrexone) is listed as an antagonist for which type of receptor?

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Question 38

Why do antidepressants often take 4 to 6 weeks to start improving symptoms?

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Question 39

Which of the following is an example of an agonist drug action as described in Table 2?

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Question 40

What does the 'A' in the pharmacokinetics acronym ADME stand for?

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Question 41

Which drug from Table 2 is used to treat ADHD and works by blocking the removal of DA and NE from the synapse?

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Question 42

According to the text, what is the most common route of drug administration?

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Question 43

The text mentions that a CDC report estimates that 1 in 88 children have been diagnosed with what disorder?

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Question 44

According to the text, which is the only group of psychotropic drugs for which there is well-established clinical data on effectiveness in children and adolescents?

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Question 45

What is the primary function of endogenous opioids, such as endorphins, according to Table 1?

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Question 46

In what way can foods, other than grapefruit juice, affect oral drug administration?

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Question 47

What does the text identify as a major complicating factor in understanding the effects of psychoactive drugs?

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Question 48

Which neurotransmitter is linked in Table 1 to both depression and arousal?

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Question 49

What is the definition of an enzyme as provided in the chapter's vocabulary?

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Question 50

Why might a doctor prescribe additional drugs to a patient who has already been prescribed one psychotropic drug?

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