The Lymphatic and Immune System

What is the approximate number of lymph nodes found throughout the human body?

Which of the following describes the function of the spleen?

Which cell type is part of the innate immune response and kills target cells by inducing apoptosis using perforins and granzymes?

What is the process called where an antibody or antimicrobial protein tags a pathogen for phagocytosis?

According to the chapter, approximately how many liters of plasma are released into the interstitial space of tissues each day due to capillary filtration?

Which structure is a sac-like chamber that receives lymph from the lower abdomen, pelvis, and lower limbs?

What are the four characteristics of inflammation as described in the hallmark of the innate immune response?

In T cell development, what is the process called where T cells that bind to self-antigens are killed by apoptosis?

Which class of antibody is the largest, usually the first made during a primary response, and is a pentamer?

What is the term for the reciprocal relationship between rising antibody levels and declining virus levels in the blood during an infection?

Type I hypersensitivity, such as a severe allergy to peanuts, is mediated by which class of antibody?

Graft-versus-host disease is a complication primarily associated with which type of medical procedure?

What is the primary function of the thymus gland?

The thoracic duct drains lymph from all of the following areas EXCEPT:

Which type of professional antigen-presenting cell is primarily responsible for bringing antigens to regional draining lymph nodes to initiate a T cell response?

What is the term for the process that eliminates immature B cells in the bone marrow that bind strongly to self-antigens?

Which antibody class is the only one that can cross the placenta to protect the developing fetus?

Delayed-type hypersensitivity (Type IV), such as the tuberculin test reaction, is primarily mediated by which cells?

An immature T cell, upon leaving the bone marrow to mature in the thymus, is referred to as what?

Mucosa-associated lymphoid tissue (MALT) is found in all of the following locations EXCEPT the:

Which of the following is a primary lymphoid organ?

What is the function of the fas ligand expressed on Natural Killer (NK) cells?

The human body is estimated to contain approximately how many lymphocytes?

Which of the following is a characteristic of the adaptive immune response, but not the innate immune response?

Which type of T cell secretes cytokines that regulate the activity of macrophages and other T cells?

The severe, systemic allergic reaction that can be fatal within 20 to 30 minutes and is treated with epinephrine is known as what?

Which two classes of antibody can function as the antigen receptor on the surface of naïve B cells?

Peyer's patches are a type of MALT found in which location?

What is the process by which a B cell changes the class of antibody it produces, such as from IgM to IgG, without changing its antigen specificity?

In a secondary adaptive immune response, compared to a primary response, the response is:

What is the term for an antigen that can activate a B cell without cytokine help from a T cell, typically due to a structure of repeated carbohydrate moieties?

Which of the following is NOT listed as a barrier defense of the immune system?

What is the primary cause of age-related immune deficiencies, known as immunosenescence?

What is the medical term for the condition where a mother negative for Rh antigen develops antibodies against her Rh-positive fetus?

T cells recognize antigens only when they are presented on the surface of a cell in association with which type of molecule?

What is the primary function of Helper T cells (Th) in the adaptive immune response?

Type III hypersensitivity reactions, such as in systemic lupus erythematosus, are caused by what mechanism?

The milky fluid called chyle, containing dietary lipids and lipid-soluble vitamins, is transported from the small intestine via which structures?

Which of the following is NOT a function of the complement system cascade?

What is the process called where an individual's immune system develops resistance to a pathogen after being exposed to a killed or weakened version of it, such as in a vaccine?

Intracellular antigens, such as those from viruses, are typically processed and presented on which class of MHC molecules?

Which autoimmune disease involves antibodies that cross-react with heart myosin following a Streptococcus infection?

What is the primary function of the tonsils?

Severe combined immunodeficiency disease (SCID) is a serious inherited condition because it affects which arms of the adaptive immune response?

Which soluble mediator of the innate immune response is a signaling molecule that allows cells to communicate over short distances?

The memory of a primary adaptive immune response is held by which two cell types?

The enzyme lysozyme, which is rich in saliva, provides a barrier defense by what mechanism?

Human Immunodeficiency Virus (HIV) primarily compromises the immune system by targeting which cell type?

What is the term for a B cell that has differentiated in response to antigen binding and is specialized to secrete soluble antibodies?

What is the primary role of eosinophils in the immune response?