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Questions

Question 1

What is the primary function of transfer RNAs (tRNAs) in protein synthesis, as described by Francis Crick's adaptor hypothesis?

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Question 2

What are the three potential reading frames in the genetic code?

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Question 3

According to the wobble hypothesis proposed by Francis Crick, which base of an mRNA codon pairs most loosely with its corresponding base in the tRNA anticodon?

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Question 4

What is the typical error rate of protein synthesis?

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Question 5

What is the primary function of the Shine-Dalgarno sequence in bacterial mRNA?

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Question 6

What is the role of the 23S rRNA in bacterial ribosomes?

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Question 7

In the process of charging a tRNA, what is the role of the two classes of aminoacyl-tRNA synthetases?

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Question 8

What is the energy cost, in terms of high-energy phosphate bonds, to form each peptide bond of a polypeptide during protein synthesis?

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Question 9

What is the function of the signal recognition particle (SRP) in eukaryotic protein targeting?

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Question 10

What is the primary mechanism by which ubiquitin targets a protein for degradation?

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Question 11

How many different amino acids does the genetic code specify, not including termination signals?

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Question 12

What is the function of the elongation factor EF-Tu in bacterial protein synthesis?

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Question 13

What happens to the signal sequence of a protein targeted to the endoplasmic reticulum?

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Question 14

What is the approximate molecular weight of the 26S proteasome in eukaryotes?

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Question 15

How does the antibiotic puromycin inhibit protein synthesis?

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Question 16

In the context of the genetic code, what does it mean for the code to be 'degenerate'?

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Question 17

What is the function of initiation factor IF-3 in bacterial protein synthesis?

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Question 18

What is the typical length of the N-terminal signal sequences that direct proteins to the ER in eukaryotes?

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Question 19

What is the function of tunicamycin?

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Question 20

In the process of protein degradation, what is the role of the 19S regulatory particle of the 26S proteasome?

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