Library/Biological and Biomedical Sciences/Lehninger Principles of Biochemistry/Hormonal Regulation and Integration of Mammalian Metabolism

Hormonal Regulation and Integration of Mammalian Metabolism

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Questions

Question 1

What are the two general classes of muscle tissue, which differ in physiological role and fuel utilization?

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Question 2

What is the primary fuel source for resting skeletal muscle?

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Question 3

Which hormone is released into the blood to prepare the muscles, lungs, and heart for a burst of activity, mediating the 'fight or flight' response?

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Question 4

What is the primary function of brown adipose tissue (BAT)?

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Question 5

What is the approximate Body Mass Index (BMI) threshold above which an individual is considered obese?

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Question 6

What is the role of the adipokine leptin in the regulation of body mass?

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Question 7

Which peptide hormone, secreted by endocrine cells in the small intestine and colon after a meal, acts on the arcuate nucleus to inhibit NPY release and reduce hunger?

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Question 8

What is the primary role of the Cori cycle?

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Question 9

What is the characteristic symptom that defines the metabolic syndrome, or syndrome X?

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Question 10

What is the primary mechanism by which sulfonylurea drugs are used to treat type 2 diabetes?

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Question 11

What is the fate of excess acetyl-CoA in the liver during prolonged fasting or in uncontrolled diabetes?

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Question 12

What is the approximate normal range for blood glucose concentration in humans?

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Question 13

In the hypothalamic regulation of appetite, which neurons are considered orexigenic (appetite-stimulating)?

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Question 14

What is the mechanism of the JAK-STAT signaling pathway triggered by leptin?

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Question 15

Which enzyme is a key target of the hormone adiponectin and plays a central role in regulating the metabolism of lipids and carbohydrates by phosphorylating other key metabolic enzymes?

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