What is the primary mechanism by which ubiquitin targets a protein for degradation?
Explanation
This question tests the understanding of the ubiquitin-proteasome system. The key concept is that ubiquitin acts as a covalent tag, forming a polyubiquitin chain on a target protein, which then serves as a signal for the protein to be recognized and degraded by the 26S proteasome.
Other questions
What is the primary function of transfer RNAs (tRNAs) in protein synthesis, as described by Francis Crick's adaptor hypothesis?
What are the three potential reading frames in the genetic code?
According to the wobble hypothesis proposed by Francis Crick, which base of an mRNA codon pairs most loosely with its corresponding base in the tRNA anticodon?
What is the typical error rate of protein synthesis?
What is the primary function of the Shine-Dalgarno sequence in bacterial mRNA?
What is the role of the 23S rRNA in bacterial ribosomes?
In the process of charging a tRNA, what is the role of the two classes of aminoacyl-tRNA synthetases?
What is the energy cost, in terms of high-energy phosphate bonds, to form each peptide bond of a polypeptide during protein synthesis?
What is the function of the signal recognition particle (SRP) in eukaryotic protein targeting?
How many different amino acids does the genetic code specify, not including termination signals?
What is the function of the elongation factor EF-Tu in bacterial protein synthesis?
What happens to the signal sequence of a protein targeted to the endoplasmic reticulum?
What is the approximate molecular weight of the 26S proteasome in eukaryotes?
How does the antibiotic puromycin inhibit protein synthesis?
In the context of the genetic code, what does it mean for the code to be 'degenerate'?
What is the function of initiation factor IF-3 in bacterial protein synthesis?
What is the typical length of the N-terminal signal sequences that direct proteins to the ER in eukaryotes?
What is the function of tunicamycin?
In the process of protein degradation, what is the role of the 19S regulatory particle of the 26S proteasome?