11. Lymphatic and Immune Systems

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Questions

Question 1

How many liters of plasma are released into the interstitial space of the tissues each day due to capillary leakage?

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Question 2

Which structure is responsible for draining lymph fluid from the right sides of the head, thorax, and right upper limb into the right subclavian vein?

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Question 3

What is the term for the age-related shrinking of the thymus gland?

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Question 4

What is the approximate rate of tissue loss per year for the thymus gland from birth until 35 to 45 years of age?

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Question 5

Which of the following is considered a primary lymphoid organ?

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Question 6

What is the primary function of the spleen, earning it the name 'filter of the blood'?

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Question 7

What are the deep grooves in tonsils called that accumulate materials and encourage pathogens to penetrate into the tonsillar tissues?

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Question 8

What type of Mucosa-associated lymphoid tissue (MALT) is especially important for immune responses against ingested substances and is found in the small intestine?

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Question 9

What is the term for the clearance of a pathogen from the body by the adaptive immune response, which does not necessarily mean a patient is getting well?

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Question 10

Which of the following is an example of a barrier defense mechanism of the immune system?

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Question 11

What type of cell is described as a circulating precursor that differentiates into either a macrophage or a dendritic cell?

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Question 12

What is the primary function of a chemokine?

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Question 13

Which of the four characteristics of inflammation is caused by histamine increasing the permeability of local capillaries, leading to plasma leakage?

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Question 14

The secondary adaptive immune response, which is stronger and faster than the primary response, is the basis for what phenomenon?

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Question 15

Which class of antibody is the only one that can cross the placenta to protect the developing fetus?

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Question 16

Which type of T cell helps to develop and regulate other immune system cells by releasing cytokines?

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Question 17

What is the defining characteristic of passive immunity?

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Question 18

Which of the following is an example of a pathogen evading the immune system through antigenic mutation?

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Question 19

In the context of immune response to cancer, what is the 'Equilibrium' stage?

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Question 20

What is the most serious form of inherited immunodeficiency, which is caused by genetic defects impairing both B cell and T cell arms of the adaptive immune response?

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Question 21

According to the text, how quickly can severe allergies causing anaphylactic shock be fatal if left untreated?

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Question 22

Which type of hypersensitivity is responsible for the reactions seen in mismatched blood transfusions and erythroblastosis fetalis?

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Question 23

What is the autoantigen targeted in Graves’ disease, leading to hyperthyroidism?

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Question 24

What is the term for a lymphocyte that has left a primary lymphoid organ but has not yet encountered an antigen?

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Question 25

What is the condition called when interstitial fluid accumulates in tissue spaces due to a damaged lymphatic system?

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Question 26

Which chemical mediators, released from mast cells during an inflammatory response, attract neutrophils from the blood by chemotaxis?

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Question 27

Which of the following describes the function of natural killer (NK) cells?

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Question 28

What type of immunity is conferred by a vaccine?

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Question 29

Graft-versus-host disease (GVHD) is a complication that occurs in which type of transplantation procedure?

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Question 30

Chronic stress, unlike short-term stress, may have what effect on the immune system?

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Question 31

Which type of hypersensitivity is described as 'delayed hypersensitivity' and takes 24 to 72 hours to develop?

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Question 32

What is the term for a firm, raised, reddened patch of skin that indicates a positive tuberculin test?

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Question 33

The autoimmune disease Myasthenia gravis targets which autoantigen, leading to debilitating muscle weakness?

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Question 34

What is the primary cell of the adaptive immune response?

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Question 35

Which antibody class is particularly associated with allergies and anaphylaxis?

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Question 36

In what location do B cells undergo nearly all of their development?

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Question 37

The thoracic duct drains a much larger portion of the body than the right lymphatic duct and begins just beneath the diaphragm in a structure called the:

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Question 38

According to the text, which type of signaling involves a chemical triggering a response in the very same cell that secreted it?

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Question 39

What is the approximate length of the spleen?

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Question 40

The HIV virus causes Acquired Immunodeficiency by steadily declining the levels of which specific cells, eventually leading to a weakened immune response?

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Question 41

What is the term for the body's ability to distinguish between self-antigens and foreign antigens?

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Question 42

Which of the following conditions is a form of cancer where malignant T and/or B lymphocytes collect in lymph nodes, the spleen, and other tissues?

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Question 43

What are interferons?

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Question 44

According to the text, a major function of tonsils is to help children's bodies perform what action regarding common environmental pathogens?

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Question 45

What happens during the 'seroconversion' phase of an HIV infection?

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Question 46

Which condition is an autoimmune disease where the immune system attacks joint capsule antigens, leading to chronic inflammation of joints?

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Question 47

How many lymph nodes are estimated to be in the human body?

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Question 48

What is the term for the process where phagocytes are attracted to infected tissues from the bloodstream?

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Question 49

Which phase of the immune response is considered the body's first line of physiological defense, occurring rapidly but with less specificity than the adaptive response?

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Question 50

What is the primary substance that causes pain during an inflammatory response by relaxing vascular smooth muscle?

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