The Innate and Adaptive Immune Systems
20 questions available
Questions
Which statement accurately distinguishes between the innate and adaptive immune systems?
View answer and explanationWhat is the general term for the microbe-associated molecules that are recognized by the innate immune system's receptor proteins?
View answer and explanationAccording to the text, approximately how many different Toll-like receptors (TLRs) does a human make?
View answer and explanationWhich Toll-like receptor (TLR) is responsible for recognizing lipopolysaccharide (LPS) on the outer membrane of Gram-negative bacteria?
View answer and explanationWhat is described as the pivotal complement component that is cleaved and activated by all three pathways of complement activation?
View answer and explanationHow do Natural Killer (NK) cells primarily distinguish virus-infected cells from healthy cells?
View answer and explanationWhich cell type is described as the crucial link between the innate and adaptive immune systems because it ingests pathogens and presents their antigens to T cells?
View answer and explanationWhat is the approximate number of lymphocytes in the human body, making the immune system comparable in cell mass to the liver or brain?
View answer and explanationWhere do T cells and B cells primarily develop, respectively, in adult mammals?
View answer and explanationWhat is the key difference between a primary and a secondary immune response to the same antigen?
View answer and explanationWhich of the following is NOT listed as a mechanism for establishing immunological self-tolerance?
View answer and explanationWhich class of immunoglobulin is the first to be made by a developing B cell and is also the major class secreted in the early stages of a primary antibody response?
View answer and explanationHow many antigen-binding sites does a secreted IgM molecule have, due to its pentameric structure?
View answer and explanationWhich immunoglobulin class is secreted in the largest quantities during a secondary immune response and is capable of crossing the placenta from mother to fetus?
View answer and explanationWhich immunoglobulin class is primarily responsible for allergic reactions like hay fever and asthma by binding to Fc receptors on mast cells?
View answer and explanationWhat is the primary function of the activation-induced deaminase (AID) enzyme in activated B cells?
View answer and explanationWhat is a key structural difference between T cell receptors (TCRs) and B cell receptors (BCRs)?
View answer and explanationTo which cells do class I and class II MHC proteins primarily present foreign peptides, respectively?
View answer and explanationWhat is the typical length of the peptides displayed in the peptide-binding groove of Class I MHC proteins?
View answer and explanationFrom where do the peptides presented by class II MHC proteins on antigen-presenting cells (APCs) mainly originate?
View answer and explanation