Cytokines and their Receptors

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Questions

Question 1

What is the size and form of the Colony-stimulating factor G-CSF (CSF-3) according to the appendix on cytokines?

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Question 2

Which cells are listed as the producers of GM-CSF (granulocyte-macrophage colony-stimulating factor)?

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Question 3

What is the effect of a knockout of the M-CSF (CSF-1) receptor?

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Question 4

According to the appendix on cytokines, what are the actions of IFN-γ?

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Question 5

What are the receptors for the cytokine IL-1α?

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Question 6

What is the described effect of an IL-1β knockout?

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Question 7

What is the primary action of IL-1 RA (receptor antagonist) as described in the appendix?

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Question 8

What is the alternative name for IL-2 provided in the appendix on cytokines?

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Question 9

What common subunit is part of the receptor for IL-3 (multicolony CSF)?

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Question 10

Which of the following are listed as producer cells for IL-4 (BCGF-1, BSF-1)?

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Question 11

What is the size and form of the cytokine IL-5 (BCGF-2)?

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Question 12

What are the components of the IL-6 receptor according to the appendix?

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Question 13

What is the described effect of an IL-7 knockout on the immune system?

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Question 14

Which of the following is an action of IL-9?

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Question 15

What is the alternative name for IL-10 listed in the appendix on cytokines?

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Question 16

What are the producer cells for the cytokine IL-11?

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Question 17

What are the sizes of the two subunits of the heterodimeric cytokine IL-12?

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Question 18

What are the described actions of the interleukin IL-13?

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Question 19

Besides IL-15, what is the alternative name for the cytokine that shares receptors with IL-2?

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Question 20

What is the molecular form of IL-16 according to the appendix?

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Question 21

Which cells are listed as producers of IL-17A (mCTLA-8)?

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Question 22

What is the size in amino acids of the cytokine IL-17F (ML-1)?

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Question 23

Which cells produce IL-18 (IGIF, interferon-α inducing factor)?

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Question 24

Which receptors are used by IL-19?

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Question 25

Which of the following cell types are producers of IL-20?

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Question 26

What is the effect of an IL-21 knockout on the immune system?

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Question 27

What is the alternative name for the cytokine IL-22?

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Question 28

What is the molecular structure of the cytokine IL-23?

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Question 29

What are the actions of IL-24 (MDA-7)?

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Question 30

What is the receptor for the cytokine IL-25 (IL-17E)?

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Question 31

Which cells are listed as producers of IL-26 (AK155)?

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Question 32

What are the producer cells for the cytokine IL-27?

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Question 33

What is the primary action of IL-28A,B (IFN-B502,3)?

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Question 34

The cytokine IL-29 (IFN-λ1) belongs to which family?

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Question 35

What is the relationship between IL-30 and IL-27 as described in the appendix?

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Question 36

Which cell type is listed as the producer of IL-31?

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Question 37

According to the appendix, what is the action of IL-32 (NK4, TAIF)?

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Question 38

What are the components of the receptor for IL-33 (NF-HEV)?

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Question 39

What is the size and form of the cytokine IL-34 (C16orf77)?

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Question 40

What is the molecular structure of the cytokine IL-35?

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Question 41

Which cells are listed as producers of the IL-36 family of cytokines (IL-36α, β, λ)?

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Question 42

What is the size and form of the cytokine IL-37?

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Question 43

What are the components of the TSLP receptor?

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Question 44

What is the described effect of a LIFR (leukemia inhibitory factor receptor) knockout?

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Question 45

What are the actions of OSM (oncostatin M)?

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Question 46

What is the size and form of TNF-α (cachectin)?

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Question 47

Which cells are listed as the primary producers of LT-α (lymphotoxin-α)?

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Question 48

What is the described action of Fas ligand (FasL)?

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Question 49

Which cells are listed as producers of Trail (AP0-2L)?

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Question 50

What is a key action of TGF-β1 as listed in the 'Unassigned' family of cytokines?

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