Chemokines and their Receptors

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Questions

Question 1

What is the common name for the chemokine with the systematic name CXCL8?

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Question 2

Which specific receptors bind the chemokine CXCL8 (IL-8)?

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Question 3

According to the table of chemokines and their receptors, on which chromosome are the genes for the chemokines GRO-alpha (CXCL1), GRO-beta (CXCL2), and GRO-gamma (CXCL3) located?

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Question 4

The footnote in Appendix IV states that if the three amino acids preceding the first cysteine residue of the CXC motif are Glu-Leu-Arg (ELR+), the chemokine is chemotactic for which cell type?

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Question 5

Which of the following is listed as a target cell for the chemokine CXCL12 (SDF-1alpha/beta)?

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Question 6

What is the specific receptor for the chemokine CCL2, also known as MCP-1?

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Question 7

The chemokine CCL11, also known as Eotaxin, primarily targets which cell types?

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Question 8

According to the footnote in Appendix IV, what is the key difference in the CXC motif that determines whether a chemokine is chemotactic for lymphocytes instead of neutrophils?

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Question 9

Which chemokine ligands bind to the atypical chemokine receptor D6?

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Question 10

To which chemokine family does Fractalkine, with the systematic name CX3CL1, belong?

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Question 11

Many chemokines in the CCL family, such as MCP-1 (CCL2), MIP-1alpha (CCL3), and RANTES (CCL5), are located on which human chromosome?

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Question 12

What is the specific receptor for the chemokine CX3CL1, also known as Fractalkine?

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Question 13

Which chemokine, also known as 6Ckine/SLC, primarily targets naive T cells, B cells, thymocytes, NK cells, and mature dendritic cells?

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Question 14

The chemokine CCL21 (6Ckine/SLC) binds to which specific receptor to attract naive T and B cells to lymphoid tissues?

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Question 15

What is the common name for the chemokine CXCL13?

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Question 16

The chemokine CXCL13 (BLC/BCA-1) is primarily involved in attracting which cell types?

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Question 17

What is the primary specific receptor for CXCL13 (BLC/BCA-1)?

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Question 18

Which chemokine, with the systematic name CCL27, is associated with skin homing memory T cells and B cells?

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Question 19

The chemokine CCL27 (CTACK) binds to which specific receptor?

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Question 20

Which atypical chemokine receptor is found on red blood cells, Purkinje cells, and blood endothelial cells, and binds various CXC and CC chemokines?

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