Chemokines and their Receptors
20 questions available
Questions
What is the common name for the chemokine with the systematic name CXCL8?
View answer and explanationWhich specific receptors bind the chemokine CXCL8 (IL-8)?
View answer and explanationAccording to the table of chemokines and their receptors, on which chromosome are the genes for the chemokines GRO-alpha (CXCL1), GRO-beta (CXCL2), and GRO-gamma (CXCL3) located?
View answer and explanationThe footnote in Appendix IV states that if the three amino acids preceding the first cysteine residue of the CXC motif are Glu-Leu-Arg (ELR+), the chemokine is chemotactic for which cell type?
View answer and explanationWhich of the following is listed as a target cell for the chemokine CXCL12 (SDF-1alpha/beta)?
View answer and explanationWhat is the specific receptor for the chemokine CCL2, also known as MCP-1?
View answer and explanationThe chemokine CCL11, also known as Eotaxin, primarily targets which cell types?
View answer and explanationAccording to the footnote in Appendix IV, what is the key difference in the CXC motif that determines whether a chemokine is chemotactic for lymphocytes instead of neutrophils?
View answer and explanationWhich chemokine ligands bind to the atypical chemokine receptor D6?
View answer and explanationTo which chemokine family does Fractalkine, with the systematic name CX3CL1, belong?
View answer and explanationMany chemokines in the CCL family, such as MCP-1 (CCL2), MIP-1alpha (CCL3), and RANTES (CCL5), are located on which human chromosome?
View answer and explanationWhat is the specific receptor for the chemokine CX3CL1, also known as Fractalkine?
View answer and explanationWhich chemokine, also known as 6Ckine/SLC, primarily targets naive T cells, B cells, thymocytes, NK cells, and mature dendritic cells?
View answer and explanationThe chemokine CCL21 (6Ckine/SLC) binds to which specific receptor to attract naive T and B cells to lymphoid tissues?
View answer and explanationWhat is the common name for the chemokine CXCL13?
View answer and explanationThe chemokine CXCL13 (BLC/BCA-1) is primarily involved in attracting which cell types?
View answer and explanationWhat is the primary specific receptor for CXCL13 (BLC/BCA-1)?
View answer and explanationWhich chemokine, with the systematic name CCL27, is associated with skin homing memory T cells and B cells?
View answer and explanationThe chemokine CCL27 (CTACK) binds to which specific receptor?
View answer and explanationWhich atypical chemokine receptor is found on red blood cells, Purkinje cells, and blood endothelial cells, and binds various CXC and CC chemokines?
View answer and explanation