According to the appendix on cytokines, what are the actions of IFN-γ?

Correct answer: Macrophage activation, increased expression of MHC molecules and antigen processing components, Ig class switching, supresses TH17 and TH2

Explanation

This question tests the knowledge of the pleiotropic actions of the cytokine IFN-γ as described in the 'Actions' column of the provided table.

Other questions

Question 1

What is the size and form of the Colony-stimulating factor G-CSF (CSF-3) according to the appendix on cytokines?

Question 2

Which cells are listed as the producers of GM-CSF (granulocyte-macrophage colony-stimulating factor)?

Question 3

What is the effect of a knockout of the M-CSF (CSF-1) receptor?

Question 5

What are the receptors for the cytokine IL-1α?

Question 6

What is the described effect of an IL-1β knockout?

Question 7

What is the primary action of IL-1 RA (receptor antagonist) as described in the appendix?

Question 8

What is the alternative name for IL-2 provided in the appendix on cytokines?

Question 9

What common subunit is part of the receptor for IL-3 (multicolony CSF)?

Question 10

Which of the following are listed as producer cells for IL-4 (BCGF-1, BSF-1)?

Question 11

What is the size and form of the cytokine IL-5 (BCGF-2)?

Question 12

What are the components of the IL-6 receptor according to the appendix?

Question 13

What is the described effect of an IL-7 knockout on the immune system?

Question 14

Which of the following is an action of IL-9?

Question 15

What is the alternative name for IL-10 listed in the appendix on cytokines?

Question 16

What are the producer cells for the cytokine IL-11?

Question 17

What are the sizes of the two subunits of the heterodimeric cytokine IL-12?

Question 18

What are the described actions of the interleukin IL-13?

Question 19

Besides IL-15, what is the alternative name for the cytokine that shares receptors with IL-2?

Question 20

What is the molecular form of IL-16 according to the appendix?

Question 21

Which cells are listed as producers of IL-17A (mCTLA-8)?

Question 22

What is the size in amino acids of the cytokine IL-17F (ML-1)?

Question 23

Which cells produce IL-18 (IGIF, interferon-α inducing factor)?

Question 24

Which receptors are used by IL-19?

Question 25

Which of the following cell types are producers of IL-20?

Question 26

What is the effect of an IL-21 knockout on the immune system?

Question 27

What is the alternative name for the cytokine IL-22?

Question 28

What is the molecular structure of the cytokine IL-23?

Question 29

What are the actions of IL-24 (MDA-7)?

Question 30

What is the receptor for the cytokine IL-25 (IL-17E)?

Question 31

Which cells are listed as producers of IL-26 (AK155)?

Question 32

What are the producer cells for the cytokine IL-27?

Question 33

What is the primary action of IL-28A,B (IFN-B502,3)?

Question 34

The cytokine IL-29 (IFN-λ1) belongs to which family?

Question 35

What is the relationship between IL-30 and IL-27 as described in the appendix?

Question 36

Which cell type is listed as the producer of IL-31?

Question 37

According to the appendix, what is the action of IL-32 (NK4, TAIF)?

Question 38

What are the components of the receptor for IL-33 (NF-HEV)?

Question 39

What is the size and form of the cytokine IL-34 (C16orf77)?

Question 40

What is the molecular structure of the cytokine IL-35?

Question 41

Which cells are listed as producers of the IL-36 family of cytokines (IL-36α, β, λ)?

Question 42

What is the size and form of the cytokine IL-37?

Question 43

What are the components of the TSLP receptor?

Question 44

What is the described effect of a LIFR (leukemia inhibitory factor receptor) knockout?

Question 45

What are the actions of OSM (oncostatin M)?

Question 46

What is the size and form of TNF-α (cachectin)?

Question 47

Which cells are listed as the primary producers of LT-α (lymphotoxin-α)?

Question 48

What is the described action of Fas ligand (FasL)?

Question 49

Which cells are listed as producers of Trail (AP0-2L)?

Question 50

What is a key action of TGF-β1 as listed in the 'Unassigned' family of cytokines?