What is the consequence of a glucose 6-phosphate dehydrogenase (G6PD) deficiency in individuals, particularly under conditions of oxidative stress?
Explanation
Glucose 6-phosphate dehydrogenase (G6PD) is a critical enzyme in the pentose phosphate pathway, responsible for producing NADPH. NADPH is essential for protecting cells against oxidative damage. A deficiency in G6PD can lead to hemolytic anemia, especially when individuals are exposed to oxidative stressors.
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