In what form are more than 95 percent of all lipids found in the plasma in the postabsorptive state, after chylomicrons have been cleared?

Correct answer: Lipoprotein

Explanation

This question clarifies the predominant form of lipid transport in the blood during the fasting state, highlighting the central role of lipoproteins in carrying cholesterol, triglycerides, and phospholipids.

Other questions

Question 1

Which enzyme is synthesized by tissues such as adipose tissue, skeletal muscle, and heart, and is transported to the surface of capillary endothelial cells to hydrolyze chylomicron triglycerides?

Question 2

What is the approximate concentration of free fatty acids in the plasma under resting conditions?

Question 3

How quickly is half of the plasma free fatty acid replaced by new fatty acid, indicating its extremely rapid rate of turnover?

Question 4

Under normal physiological conditions, how many molecules of fatty acid typically combine with a single molecule of albumin for transport in the blood?

Question 5

Which type of lipoprotein is derived from the removal of almost all triglycerides from Intermediate-Density Lipoproteins (IDLs), resulting in a high concentration of cholesterol?

Question 6

What is the primary function of Very Low Density Lipoproteins (VLDLs)?

Question 8

What process occurs in the mitochondria to degrade fatty acids by progressively releasing two-carbon segments as acetyl-CoA?

Question 9

What is the net gain of ATP molecules from the complete oxidation of one molecule of stearic acid?

Question 10

Which condition, resulting from the accumulation of acetoacetic acid, β-hydroxybutyric acid, and acetone, occurs as a consequence of starvation or in persons with diabetes mellitus?

Question 11

What is the primary product of carbohydrate metabolism that is required to bind with acetyl-CoA for it to be processed in the citric acid cycle, a deficiency of which limits the oxidation of ketone bodies?

Question 12

What percentage of the original energy in glucose is transferred to stored triglycerides during the process of fat synthesis, with the remainder lost as heat?

Question 13

Which hormone's absence severely impairs the synthesis of fats from carbohydrates, primarily because glucose entry into fat and liver cells is unsatisfactory?

Question 14

Which two hormones, released by the adrenal medullae during heavy exercise, directly activate hormone-sensitive triglyceride lipase in fat cells, causing rapid mobilization of fatty acids?

Question 15

By far the most abundant non-membranous use of cholesterol in the body is the formation of what substance in the liver?

Question 16

A diet high in which type of fat is described as increasing blood cholesterol concentration by 15 to 25 percent?

Question 17

What is the primary substance that makes the skin highly resistant to the absorption of water-soluble substances and helps prevent water evaporation?

Question 18

What is the initial event in the development of atherosclerosis, which increases the expression of adhesion molecules on endothelial cells?

Question 19

Macrophage foam cells, which form fatty streaks in atherosclerosis, are created when macrophages ingest and oxidize which type of lipoprotein?

Question 20

What is the primary function of apolipoprotein-E on the surface of chylomicron remnants?

Question 21

What is the term for fatty acids that are bound to albumin in the plasma, distinguishing them from fatty acids that exist as esters of glycerol or cholesterol?

Question 22

What is the primary location for the formation of almost all lipoproteins in the body?

Question 23

Fat cells (adipocytes) in adipose tissue are modified fibroblasts that can store almost pure triglycerides in quantities as great as what percentage of their entire cell volume?

Question 24

Which of the following is NOT a principal function of the liver in lipid metabolism?

Question 25

The degradation and oxidation of fatty acids, a process that requires carnitine as a carrier for entry, occurs exclusively in which cellular organelle?

Question 26

In the process of beta-oxidation, the beta carbon of the fatty acyl-CoA molecule binds with which molecule to become oxidized?

Question 27

After beta-oxidation of fatty acids in the liver, two molecules of acetyl-CoA condense to form what substance, which is then transported in the blood to other cells for energy?

Question 28

Under what circumstance does the body adapt to use far more acetoacetic acid than usual, preventing the development of ketosis?

Question 29

The glycerol portion of triglycerides, used in their synthesis, is furnished by what product derived from the glycolytic scheme of glucose degradation?

Question 30

When excess carbohydrates are available, they are said to have a 'fat-sparing' effect. What is the primary mechanism for this effect?

Question 31

Which of the following is NOT one of the major types of body phospholipids mentioned in the text?

Question 32

Which phospholipid is necessary to initiate the blood clotting process because it is the main component of thromboplastin?

Question 33

What percentage of the cholesterol circulating in the lipoproteins of the plasma is in the form of cholesterol esters?

Question 34

What is the effect of a lack of insulin or thyroid hormone on blood cholesterol concentration?

Question 35

According to the text, which cells are responsible for producing endogenous cholesterol that circulates in the plasma lipoproteins?

Question 36

What is the general term for thickened and stiffened blood vessels of all sizes?

Question 37

What is the turnover rate of triglycerides in fat cells, indicating the dynamic state of storage fat?

Question 38

Which substance is required to maintain the glycerol portion of triglycerides, and its insufficiency in fat cells can promote the hydrolysis of triglycerides?

Question 39

Which statement accurately describes Intermediate-density lipoproteins (IDLs)?

Question 40

What is the principal reason that the liver cells are more capable of desaturating fatty acids than other tissues?

Question 41

After being transported into an active tissue, what is glycerol immediately converted into to enter the glycolytic pathway?

Question 42

What is the net reaction in the citric acid cycle for each molecule of acetyl-CoA that is degraded?

Question 43

In a person with severe diabetes mellitus or during starvation, why do large quantities of triglycerides appear in the liver?

Question 44

What is the term for the fatty lesions that develop on the inside surfaces of arterial walls in atherosclerosis?

Question 45

After triglycerides are removed from chylomicrons in the circulation, what are the remaining cholesterol-enriched particles called?

Question 46

What is the total concentration of lipoproteins in the plasma on average?

Question 47

Which hormone has a ketogenic effect similar to, but weaker than, that of ACTH and glucocorticoids?

Question 48

An intrinsic feedback control system for cholesterol synthesis involves the inhibition of which essential enzyme when dietary cholesterol intake increases?

Question 49

What are the first two steps of the two-step process for synthesizing fatty acids from acetyl-CoA?

Question 50

The final stage of atherosclerosis, referred to as 'hardening of the arteries,' involves the precipitation of what substance with the lipids in the plaques?