What is the function of CD52, which is targeted by therapeutic antibodies to deplete T cells from bone marrow?
Explanation
Despite being a prominent therapeutic target for lymphocyte depletion (using drugs like alemtuzumab), the precise physiological function of the CD52 antigen itself remains unknown, as noted in the appendix.
Other questions
What is the primary function of the CD2 antigen, also known as T11 or LFA-2?
According to the appendix on CD antigens, what are the molecular weights in kDa for the γ, δ, and ε chains of the CD3 antigen?
On which of the following cell populations is the CD4 antigen expressed?
What is the function of the CD5 antigen found on thymocytes and T cells?
Besides T8, what are the other names listed for the CD8 antigen?
The CD9 antigen is part of which protein family?
What is the function of CD10, also known as CALLA?
The CD11a antigen is a subunit of integrin LFA-1. Which molecules does it bind to?
What are the other names listed for the CD11b antigen?
What is the molecular weight of the CD11c antigen as listed in the appendix?
What is the described function of CD14, which is expressed on myelomonocytic cells?
CD15s, found on leukocytes and endothelium, functions as a ligand for which molecules?
What is the function of CD16a (FcγRIIIa), which is expressed on NK cells?
CD18, the integrin β2 subunit, is found on leukocytes. Which alpha subunits does it associate with?
CD19 on B cells has a key function as part of a complex. Which other molecules does it form this complex with?
What is the proposed function of CD20, which is found on B cells?
CD21, also known as CR2, functions as a receptor for which two entities?
What is the function of CD23, also known as FcεRII?
The CD25 antigen, expressed on activated T cells and other cells, is also known by what name?
What is the enzymatic function of CD26, which is highly expressed on Treg cells?
The CD27 antigen functions as a co-stimulator for T and B cells by binding to which molecule?
As the receptor for co-stimulatory signal 2, which two molecules does CD28 bind to for the activation of naive T cells?
The CD30 antigen, which is a member of the TNF receptor family, enhances B and T cell proliferation by binding to which ligand?
What is the function of CD31, also known as PECAM-1?
The CD32 antigen is described as what type of receptor?
CD34, expressed on hematopoietic precursors, functions as a ligand for which molecule?
CD35, also known as Complement Receptor 1 (CR1), binds to which complement components?
What is the enzymatic function of CD38, which is expressed on early B and T cells?
CD40, found on B cells and macrophages, receives a co-stimulatory signal by binding to which ligand?
What is another name for CD43, which is expressed on leukocytes but not resting B cells?
What is the primary enzymatic function of CD45, which is found on all hematopoietic cells?
The CD45RO isoform, a marker for memory T cells, is characterized by containing which exons?
CD47, which is expressed on all cells, functions as an adhesion molecule by acting as a receptor for which molecule?
What is another name for the CD49d antigen, which is an α4 integrin?
CD54, also known as ICAM-1, binds to which two integrins?
What is the function of CD55, also known as Decay accelerating factor (DAF)?
What is the primary function of CD59, also known as Protectin?
What is another name for CD62E, which is expressed on the endothelium?
CD64 (FcγRI) is described as a high-affinity receptor for which immunoglobulin class?
What is the function of the CD69 antigen, which is also known as the Activation Inducer Molecule (AIM)?
The CD71 antigen, expressed on all proliferating cells, is also known as what?
What is the function of the CD79α and β chains?
CD80, also known as B7.1, is a co-stimulator that serves as a ligand for which two T-cell receptors?
The CD88 antigen functions as a receptor for which complement component?
What is the well-known other name for the CD90 antigen, which is expressed on human prothymocytes?
Which CD antigen, also known as Apo-1 or Fas, induces apoptosis when it binds its ligand?
What is the molecular weight of the CD86 antigen, also known as B7.2?
What is the function of the CD89 antigen, also known as FcαR?
CD103 is described as which type of integrin?